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DSPy vs Mastra

Our take

Pick DSPy if python teams who will write signatures and a metric and already have a model API key. Pick Mastra if typeScript teams who will run Node and already have provider keys.

DSPy

DSPy

MIT Python framework for programming

Best for

DSPy A maintainable LM program in a repo

Mastra Ship an agent in Node/Next

Free plan

DSPy $0

Mastra $0 · you bring model keys

Lowest paid

DSPy Not published by the vendor

Mastra Persistent server (24/7) $100

Coding agent

DSPy

Mastra Agents + tools

Runs where

DSPy Hosted

Mastra Hosted

Watch out

DSPy You bring the model bill

Mastra Framework $0 is not tokens

Last checked

DSPy 2026-10-22 · github.com/stanfordnlp/dspy/blob

Mastra 2026-10-22 · mastra.ai/pricing

Which one, then?

Pick DSPy if

python teams who will write signatures and a metric and already have a model API key.

Read the DSPy page

Pick Mastra if

typeScript teams who will run Node and already have provider keys.

Read the Mastra page

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