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Agno vs Mastra

Our take

Pick Agno if python teams who will run AgentOS themselves and only pay when the control plane points at a live deploy. Pick Mastra if typeScript teams who will run Node and already have provider keys. Skip Agno if builders who want a hosted agent loop with no runtime to operate (CrewAI Cloud, or a single-file Pydantic AI script).

Agno

Agno

Python agents + AgentOS. Runtime

Best for

Agno Own the runtime

Mastra Ship an agent in Node/Next

Free plan

Agno $0 · /month. Unlimited usage and retention. Control plane against a local AgentOS. Any framework tag on the card (Agno SDK, LangGraph, Claude Code). Community support

Mastra $0 · you bring model keys

Lowest paid

Agno Pro $150/mo

Mastra Persistent server (24/7) $100

Coding agent

Agno Agent / Team / Workflow primitives

Mastra Agents + tools

Runs where

Agno Hosted

Mastra Hosted

Watch out

Agno Free is local

Mastra Framework $0 is not tokens

Last checked

Agno 2026-10-22 · agno.com/pricing

Mastra 2026-10-22 · mastra.ai/pricing

Which one, then?

Pick Agno if

python teams who will run AgentOS themselves and only pay when the control plane points at a live deploy.

Read the Agno page

Pick Mastra if

typeScript teams who will run Node and already have provider keys.

Read the Mastra page

Other comparisons